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If you’re even remotely interested in skincare, you most likely have heard of hyaluronic acid (HA) by now. It is mentioned everywhere and anywhere, cropping up in countless products and treatments. But what exactly is HA, and why has it managed to push its way onto everyone’s lips?Hyaluronic acid is a naturally occurring substance in the body, with almost half of the body’s stores found in the skin. It acts like a molecular sponge, holding up to 1000 times its weight in water. This remarkable ability to attract and retain begins to answer the question of why seems to be everywhere. Its hydration properties.
As time goes on for us, our skin’s HA levels gradually but surely deplete, leading to dryness, fine lines, and loss of firmness. This is where HA steps in, in skincare and of course, dermal fillers. Through the act of replenishing the skin’s HA content, combatting some of the ageing follows on, and following on from that, more youthful skin.
At The Doctors Laser Clinic, we know all about HA. We aim to harness its potential whenever we can, by providing our patients a range of treatments to to plump, hydrate, and rejuvenate the skin.
What is Hyaluronic Acid?
Hyaluronic acid (HA) is an inherent glycosaminoglycan polysaccharide composed of alternating residues of D-glucuronic acid and N-acetyl-D-glucosamine. This mouthful of a substance is found throughout the body’s connective, epithelial, and neural tissues. The average 70 kg person has roughly 15 grams of HA in their body, one-third of which is turned over daily.The amazing properties and functions of hyaluronic acid
- Excellent water retention capabilities, binding up to 1000 times its weight in water, allowing HA to intensely hydrate and lubricate tissues.
- Present in high concentrations in the skin (dermis and epidermis), eyes, and joints. The skin is the biggest beneficiary of HA.
- Acts as a cushioning and lubricating agent in joints and other tissues. The slippery, gel-like consistency of HA allows joints to move smoothly.
- Plays a vital role in wound healing by regulating inflammation and stimulating tissue repair.
- Provides volume and hydration to the skin,
- Transports essential nutrients to cells.
- Potential anti-ageing and anti-wrinkle effects when applied topically or injected into the skin.
Where is Hyaluronic Acid Found?
Hyaluronic acid is widely distributed throughout the body’s tissues. The largest amounts are found in the skin, within which, HA is present in both the dermis and epidermis. In the dermis, HA is a major component of the extracellular matrix (ECM). Its part is to hydrate and plump the skin by binding water molecules. In the epidermis, HA is found mainly in the ECM of the upper spinous and granular layers. In the basal layer, HA is predominantly intracellular. The HA-rich area in the dermis obtains water from the moisture-rich dermis. The lipid-rich stratum granulosum acts as a barrier to prevent water loss. With regards to other parts of the body, high concentrations of HA are also present in: Eyes: HA is a major component of vitreous humour and aqueous humour, helping maintain eye shape and shock absorption. Joints: HA is found in the synovial fluid, acting as a lubricant and shock absorber in joints such as the knees. Connective tissues: As part of the ECM, Hyaluronic acid is widely distributed throughout the body’s tissues. Other areas where HA is found include:- Umbilical cord
- Lungs
- Aorta
- Prostate
- Brain



